LexisNexis cuts 500 jobs, report says

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Law Technology News has reported LexisNexis has slashed about 500 workers across four offices, including Dayton.

The Dayton-area operations of LexisNexis have apparently been hit with some layoffs, but it is unclear how many local jobs were actually lost.

Law Technology News has reported the professional information company ? part of Reed Elsevier ? has slashed about 500 workers across four offices, including Dayton. Click here to read more.

The company declined to provide details about how many jobs were cut in Dayton, but released the following statement:

?LexisNexis continuously reviews its needs, operations and other factors to identify what resources and services are necessary to optimally support our customers and improve business operations. As a result of this ongoing process, we regularly build teams in certain areas of the business and reduce in others to be able to deliver next-generation solutions to customers. On balance, the total number of employees across the LexisNexis business remains consistent with prior years.?

It continued, ?Our company has a long history of operations and innovation in Ohio. The Dayton, Ohio (Miamisburg) site continues to be the largest Reed Elsevier and LexisNexis site globally. We remain committed to our flagship facility in Dayton and LexisNexis is making tremendous investments in our business and technology in Dayton with our New Lexis initiatives, which include the Lexis Advance product among others.?

LexisNexis has two divisions: Legal & Professional, which employs thousands in the Dayton region; and LexisNexis Risk Solutions, which is headquartered in Georgia. The company recently reported having 3,600 employees locally, making it the sixth largest employer in the Dayton region, according to Dayton Business Journal research.

A year ago, the company reported having 3,400 local employees.

E-mail jcogliano@bizjournals.com. Call (937) 528-4424. Twitter.com/joecogDBJ

Source: http://feeds.bizjournals.com/~r/vertical_47/~3/GpkDtnRYL04/lexisnexis-cuts-500-jobs-report-says.html

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Bus crash in southern Italy kills 38 people

ROME (AP) ? An Italian tour bus plowed through cars, crashed through the side wall of a highway bridge and plunged into a ravine, killing at least 38 people, authorities said Monday.

Rescuers wielding electric saws cut through the twisted wreckage of the bus looking for survivors overnight, and state radio quoted a local police chief as saying the bus driver was among the dead.

The bus lost control near the town of Monteforte Irpino in Irpinia, a largely agricultural area about 60 kilometers (40 miles) inland from Naples and about 250 kilometers (160 miles) south of Rome, hitting several cars before plunging some 30 meters (100 feet) off a viaduct on Sunday night.

It was not immediately clear why the bus driver lost control of the vehicle, but prosecutors were investigating technical problems and had ordered an autopsy on the driver.

Italy's Prime Minister Enrico Letta described the crash as a "dramatic moment" for his entire country.

"We are deeply pained by this tragedy that has touched many families and many children," Letta said from Athens, where he met with Greek Prime Minister Antonis Samaras.

A reporter for Naples daily Il Mattino, Giuseppe Crimaldi, told Sky TG24 TV from the scene that some witnesses told him the bus had been going at a "normal" speed on the downhill stretch of the highway when it suddenly veered and started hitting cars. Some witnesses thought they heard a noise as if the bus had blown a tire.

"All possible causes are under examination. It could be a combination of causes," Avellino Highway Police Chief Salvatore Imparato said on Sky TG24.

The bus was carrying a group of weekend holidaymakers from the town of Pozzuoli, on the coast east of Naples. The group had arrived at a hotel on Friday afternoon, and had spent the weekend visiting the spa and an early home of Padre Pio, a late mystic monk popular among Catholics, Michele Montagna, the manager of the hotel, told Sky TG24.

Relatives visited a makeshift morgue in a middle school to identify the dead on Monday. The bus, meanwhile, was towed from the site to be examined for possible malfunctions.

Firefighters extracted 37 bodies from the wreckage. Most of the dead were found inside the mangled bus, which lay on its side, while a few of the victims were pulled out from underneath the wreckage, state radio and the Italian news agency ANSA reported. One person died at the hospital.

At least 10 people, including five children, remained hospitalized on Monday.

Cars that were hit by the bus stood on the highway. One car's rear was completely crumpled, while another was smashed on its side. It was not immediately known if anyone in those cars had been injured.

___

Salvatore Laporta and Gregorio Borgia contributed to this report from Monteforte Irpino, Italy. Derek Gatopoulos contributed from Athens.

Source: http://news.yahoo.com/bus-crash-southern-italy-kills-38-people-100907834.html

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Molecular Robots To Deliver Better Targeted Therapies For Cancer, Autoimmune Diseases

Molecular robots composed of organic materials may soon offer targeted therapies for diseases such as cancer and rheumatoid arthritis, whose treatments often resemble a Faustian bargain with life itself.

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Damned if you do, damned if you don't.

These contemporary therapeutics for cancer and autoimmune diseases seem also more like cellular carpet-bombing in comparison to precision-guided "smart bombs" envisioned by medical scientists. A mixture of antibodies and short strands of DNA, so-called molecular automata would target disease-causing cells while leaving healthy cells alone.

The short strands of DNA, called oligonucleotides, can easily be tailored by scientists in a laboratory for any customized sequence, according to a collaboration of American researchers publishing Sunday in the journal Nature Nanotechnology.

"This is a proof of concept study using human cells," Sergei Rudchenko, director of flow cytometry at Hospital for Special Surgery in New York City, told reporters. "The next step is to conduct tests in a mouse model of leukemia."

In the study, Rudchenko and his colleagues teamed with researchers at nearby Columbia University to design molecular robots capable of identifying multiple receptors on cell surfaces, thereby discerning between different subpopulations of cells. Investigators experimented with white blood cells, which all carry the CD45 receptor but differentiate into subtypes carrying receptors CD20, CD3, or CD8.

The automata they created each carried an antibody component with a receptor for one of the white blood cell subtypes, as well as a DNA component tailored to closely match other robots carrying other variances of the antibody.

When mixed into blood from healthy donors, the robots of varying antibody components binded to their respective receptors. At the same time, the DNA components of varying robots nearby recognized their close cousins, triggering a cascading reaction. DNA bits ripped apart and joined in more complementary patterns, forming a new, unique strand like a Transformer toy from the 1980s.

Moreover, investigators also demonstrated the ability to program DNA strands to fluoresce when exposed to a solution, literally highlighting the cells for targeted therapy.

Maria Rudchenko, a research associate at the hospital, described the findings. "The automata trigger the growth of more strongly complementary oligonucleotides," she told reporters. "The reactions occur fast: In about 15 minutes, we can label cells."

Researchers plan to next test the technique in an animal model, preparing ultimately for human clinical trials leading to improved chemotherapy and drug agents for autoimmune disease.

Source: Rudchenko, Sergei. Molecular Robots Can Help Researchers Build More Targeted Therapeutics.?Nature Nanotechnology. 2013.

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Source: http://www.medicaldaily.com/articles/17860/20130728/molecular-robots-offer-better-targeted-therapies-cancer.htm

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STATE HOUSE NEWS: Study predicts minimum wage hike will cost jobs, cut economic output

While the House and Senate were busy?Wednesday?finalizing a tax-raising transportation funding bill, the makings of the next big debate on Beacon Hill were taking shape outside the State House walls.

Advocates for a minimum wage increase gathered to announce their plans to push for a ballot question in 2014 to raise the minimum wage to $11 an hour if the Legislature doesn?t act before then, while the National Federation of Independent Business released a study predicting that such a wage hike by 2015 tied to inflation could cost the state nearly 63,000 jobs over the next 10 years and reduce economic output by $45 billion.

The report prepared by the NFIB Research Foundation in Washington suggested that the annual labor cost per employee for small business owners could grow $4,000 to $6,000 per employee, depending on whether the wage is indexed to inflation and at what rate it grows.

?This proposal would hit the economy like a wrecking ball and we think it?s important for lawmakers to understand the potential consequences before they adopt it,? said?NFIB State Director Bill Vernon.? ?The bottom line is that Massachusetts will have tens of thousands fewer jobs, which means fewer opportunities for workers on the lowest rungs of the ladder.?

The report modeled a bill filed by Rep. Antonio Cabral that would increase the minimum wage in Massachusetts from $8 to $11 in two steps by 2015. Sen. Marc Pacheco has filed similar legislation to raise the wage rate to $11 over three years.

?It?s just not anywhere close to being accurate. It?s what they?ve said in the past and it has never come to fruition,? Pacheco said, responding to the report. ?The same groups opposed to the minimum wage were also in opposition to passing health care reform in Massachusetts. They were also for the most part in opposition to passing new sets of energy legislation. States that we compete against did not do what we did, and we?ve created more jobs than they have.?

Pacheco would like to see his bill pass the Legislature this session, but if not he said he would be ?all for? putting a question to raise the wage rate on the ballot in 2014. ?I think the citizens of Massachusetts are far and away ahead of the political leaders, in this case,? Pacheco said.

The prospects of fighting a ballot question has opposed business groups on edge. ?I?m always concerned. Clearly it?s a difficult issue politically. It?s a difficult issue for me to get across to the general public,? Vernon said.

Rep. Thomas Conroy and Sen. Daniel Wolf, co-chair the legislative committee that is weighing minimum wage proposals this session, said they are still in ?learning mode? and welcome reports like the NFIB study, even if it contradicts much of what they?re read to date.

The Wayland Democrat said he is not working under any timeline for a recommendation from the Committee on Labor and Workforce Development, but Senate President Therese Murray has expressed an interest in addressing the ?living wage.?

?We have been reading a lot of economic analysis and reports from academics and think tanks. Less from the business community, so I welcome those. But a lot of the reports point to either growth or no real effect on the economy or jobs. No deleterious effect,? Conroy said.

Over the past decade, the state?s minimum wage has climbed 18.5 percent from $6.75 in 2003 to $8 today. The last increase came in 2008 when it climbed from $7.50. The NFIB study reports 62,000 workers in Massachusetts earning at or below the minimum wage, which could climb to as high as $15 an hour by 2023 if indexed to a cost of living rate that grows 4 percent a year.

Vernon said a wage trend like that forecast in the study could turn problems like low teenage employment into a ?full-blown crisis.?

The report estimates that 58 percent of the jobs lost, even if the minimum wage isn?t tied to inflation, will come from small businesses with fewer than 500 employees.

Wage hike supporters dismiss the warnings by business groups as red herrings, but Vernon said the consequences are real. ?The evidence is contrary. You see in Massachusetts, a lot of these jobs lost are jobs not created. Our job growth is anemic and has been for a decade now. There might be a little bit of an increase now, but we haven?t increased the minimum wage yet,? Vernon said.

According to the Massachusetts Budget and Policy Center, the minimum wage has increased six times since 1995, and each time employment growth in industries with high concentrations of minimum wage workers has been more positive than total employment growth, and ?markedly higher? than growth in sectors with low concentrations of minimum wage workers.

Steven Tolman, president of the Massachusetts AFL-CIO, called the NFIB report findings ?bogus, fraudulent and misleading.? ?These are the same stupid arguments we?ve heard since I was in the Legislature,? said Tolman, who left the Senate in 2011.

Tolman, a Brighton Democrat, said that even through a recession workers higher up the pay-scale ladder have received raises from their employers without crippling economic recovery and job growth.?

?The bottom line is you can make numbers and figures work out to whatever conclusion you?re trying to reach. The hardworking people making $8 an hour haven?t had a raise in five years and someone wants to begrudge them a $1 raise. That is unbelievable,? Tolman said.

The minimum wage debate isn?t just taking place in Massachusetts. The Maine Legislature recently voted to increase its state wage from $7.50 to $9 by 2016, but could not muster the votes necessary to override a veto of the bill by Republican Gov. Paul LePage.

President Barack Obama also called for increasing the federal minimum wage to $9 in his State of the Union address this year, an idea at the time that sounded more palatable to groups like the Retailers Association of Massachusetts which worries about remaining competitive with other states.

In Washington, D.C.?on Wednesday, several business owners from around the country joined New York Sen. Kirsten Gillibrand, Sen. Bob Casey, of Pennsylvania and Rep. George Miller, of California, and Rep. Donna Edwards of Maryland to announce the formation of Business for a Fair Minimum Wage.

Suggesting that the federal minimum wage of $7.25 is lower today than it was in 1956 when adjusted for inflation, the business owners argued that paying employees a livable wage improves productivity and morale and reduces turnover, saving owners the cost of training new employees.

Others reports have suggested increasing rates of pay for employees will attract more qualified workers to Massachusetts and create more disposable income that employees will spend, thus helping the economy.

Pacheco predicted that in 20 years, if the minimum wage issue is not put to rest by tying it to inflation, groups like the NFIB will be back with another identical study warning that businesses can?t afford it. ?I?m trying to deal with facts. They?re trying to deal with myths that they keep putting out there and just never come true,? Pacheco said.

Source: http://www.wickedlocal.com/stoughton/news/x273440783/STATE-HOUSE-NEWS-Study-predicts-minimum-wage-hike-will-cost-jobs-cut-economic-output?rssfeed=true

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Obama to begin new series of economic addresses

WASHINGTON (AP) ? Drawing renewed attention to the economy, President Barack Obama will return this week to an Illinois college where he once spelled out a vision for an expanded and strengthened middle class as a freshman U.S. senator, long before the Great Recession would test his presidency.

The address Wednesday at Knox College in Galesburg, Ill., will be the first in a new series of economic speeches that White House aides say Obama intends to deliver over the next several weeks ahead of key budget deadlines in the fall. A new fiscal year begins in October, and the government will soon hit its borrowing limit.

The speech comes just a week before Congress is scheduled to leave for its monthlong August recess and is designed to build public pressure on lawmakers in hopes of averting the showdowns over taxes and spending that have characterized past budget debates.

In his economic pitch, Obama will talk about efforts to expand manufacturing, sign up the uninsured for health care coverage, revitalize the housing industry and broaden educational opportunities for preschoolers and college students. He will also promote the economic benefits of an immigration overhaul.

The White House is promoting the speech as part of an arc of economic messages from the president that began at Knox College in 2005, when Obama was in his first year in the Senate. Since then, Obama has sought to raise the profile of his economic agenda with periodic speeches, including one at Georgetown University in Washington in 2009 and one in Osawatomie, Kan., in 2011. The White House posted a video highlighting Obama's previous economic addresses.

The president will also speak Wednesday at the University of Central Missouri in Warrensburg, Mo.

Obama's focus on the economy comes as he has experienced a degree of success with the Senate, which passed an overhaul of immigration laws and unclogged a Republican blockade against several presidential nominations. It also reflects a belief at the White House that the administration has been able to manage a series of confrontations with Congress over the Internal Revenue Service, phone surveillance of Americans and the deadly attack on the U.S. consulate in Benghazi, Libya.

"The president thinks Washington has largely taken its eye off the ball on the most important issue facing the country," Obama senior adviser Dan Pfeiffer said Sunday evening in a message sent to the White House's public email list. "Instead of talking about how to help the middle class, too many in Congress are trying to score political points, refight old battles and trump up phony scandals."

Obama's agenda still faces stiff opposition in the House, where Republicans have a majority. On immigration, for example, Speaker John Boehner has said the House will not pass the Senate bill and, instead, intends to deal with the issue on a piecemeal basis.

Obama is pushing to end the federal budget cuts that kicked in this year so they don't extend into the next fiscal year. That could create a showdown with congressional Republicans in September, as the end of the current fiscal year approaches. Some Republicans also want more deficit reduction as a price for raising the debt ceiling, a bargain Obama says he will not make.

Republicans are fundamentally opposed to Obama's mix of budget cuts and tax increases. It wasn't until after last year's election that Republicans agreed to increase taxes for the wealthiest Americans in a deal that kept taxes for most Americans at rates set during the administration of President George W. Bush.

Appearing on CBS' "Face the Nation" Sunday, Boehner said the way to get the economy moving again is by stopping unnecessary regulations and bringing the federal deficit under control.

Describing "this new normal of slow economic growth, no increase in jobs that are available, wages are being basically frozen," Boehner said: "We're squeezing the middle class. And I would argue the president's policies are getting in the way of the economy growing, whether it's Obamacare, whether it's all these needless regulations that are coming out of the government."

Obama has some wind at his back as the economy continues its recovery from the recession that began during the Bush administration. Housing is coming back, the stock market is on an upswing and consumer confidence is generally higher. But unemployment, while down from a peak of 10 percent in 2009, remains high at 7.6 percent and economic growth remains modest.

Pfeiffer said Obama will unveil some new ideas, outline steps Congress can take and identify measures he can initiate on his own.

"He'll talk about the progress we've made together, the challenges that remain and the path forward," Pfeiffer said.

Source: http://news.yahoo.com/obama-begin-series-economic-addresses-000143541.html

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Gov?t finalising family visit to prisoners in Israel

by Hani Hazaimeh | Jul 21, 2013 | 21:50 Updated: Jul 21, 2013 | 23:08

In this photo, taken on May 28, Reem Hammad (left), daughter of prisoner Alaa Hammad, participates in a sit-in organised by families of Jordanians imprisoned in Israel near the Prime Ministry in Amman (JT photo)

AMMAN ? The Foreign Ministry is making the final arrangements for a visit by the families of Jordanian prisoners in Israel, a senior official said.

?We are almost there,? said Foreign Minister Nasser Judeh in remarks to The Jordan Times.?

He said his ministry is following up closely on the situation of the five hunger-striking prisoners, stressing that Abdullah Barghouthi is not in a coma as media reports quoted activists as saying.

The health condition of Barghouthi, who is serving 67 life sentences, is stable and is observing Ramadan, while the other hunger strikers are ?in good condition?, according to the minister.

A total of 125 Jordanians are held in Israeli jails, according to Palestinian Minister of Prisoners Affairs Issa Qaraqe in an interview last week with The Jordan Times.?

The last group visit arranged for families of Jordanians behind bars in Israel was in 2008.

Judeh said he will keep the concerned House panels abreast with updates on the prisoners issue.

Meanwhile, the minister announced that seven Jordanians will be released from Iraqi prisons ?soon?.?

Source: http://jordantimes.com/govt-finalising-family-visit-to-prisoners-in-israel

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